When a man drinks a cup of wine that contains one-quarter log of wine, he loses a quarter of his sense; if he drinks two cups he loses two parts of his mind; when he drinks three cups he loses three parts of his mind, his heart becomes mad, and he begins to speak strangely. When he drinks a fourth cup, he goes totally out of his mind, his kidneys are destroyed, his heart goes mad and his tongue ceases to function--he tries to speak and cannot, as his tongue is gloomy.


(Numbers Rabbah 10; Tanhuma 8)